In the US, Tolvaptan (tolvaptan systemic) is a member of the drug class vasopressin antagonists and is used to treat Euvolemic Hyponatremia and Hyponatremia.
US matches:
- Tolvaptan
Scheme
Rec.INN
ATC (Anatomical Therapeutic Chemical Classification)
C03XA01
CAS registry number (Chemical Abstracts Service)
0150683-30-0
Chemical Formula
C26-H25-Cl-N2-O3
Molecular Weight
448
Therapeutic Categories
Diuretic agent
Treatment of heart failure
Treatment of hyponatremia
Vasopressin V2 receptor antagonist
Chemical Names
(+-)-4'-[(7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-o-tolu-m-toluidide (WHO)
7-Chloro-5-hydroxy-1-[2-methyl-4-(2-methylbenzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-1-benzazepine
Benzamide, N-[4-[(7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methyl- (USAN)
N-(4-{[(5R)-7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-H-1-benzazepin-1-yl]carbonyl}-3-methylphenyl)-2-methylbenzamide (IUPAC)
N-{4-[(6R)-9-chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl]-3-methyl-phenyl}-2-methyl-benzamide
Foreign Names
- Tolvaptanum (Latin)
- Tolvaptan (German)
- Tolvaptan (French)
- Tolvaptán (Spanish)
Generic Names
- Tolvaptan (OS: USAN, JAN)
- OPC-41061 (IS)
- UNII-21G72T1950 (IS)
Brand Names
- Samsca
Otsuka, Germany; Otsuka, Sweden; Otsuka, United States; Otsuka Pharmaceuticals, United Kingdom
International Drug Name Search
Glossary
| IUPAC | International Union of Pure and Applied Chemistry |
| IS | Inofficial Synonym |
| JAN | Japanese Accepted Name |
| OS | Official Synonym |
| Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
| USAN | United States Adopted Name |
| WHO | World Health Organization |
Click for further information on drug naming conventions and International Nonproprietary Names.